Towards taxane analogues synthesis by dienyne ring closing metathesis‡

Literature Information

Publication Date 2016-08-18
DOI 10.1039/C6QO00321D
Impact Factor 5.281
Authors

S. Pérez-Estrada, N. Sayar, J. R. Granja


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Abstract

Herein we report the facile construction of taxadiene analogues by ring closing metathesis of dienynes built on a cyclohexenone with a natural configuration at C1 and its further transformation to incorporate most of the key functional groups of taxol.

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Organic Chemistry Frontiers

Organic Chemistry Frontiers
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