Non-covalent organocatalysis in asymmetric oxidative C(sp3)–H bond functionalization – broadening C–H bond coupling reactions
Literature Information
Publication Date
2015-12-08
DOI
10.1039/C5QO00347D
Impact Factor
5.281
Authors
Sebastian Stockerl
View Original
Abstract
Among the current huge development activities in C–H functionalization, asymmetric oxidative C(sp3)–H bond coupling strategies have remained underrepresented. Beyond the initial examples using chiral metal complexes, the use of organocatalysis provides a new direction for the design of new asymmetric C–H bond cross-coupling reactions. This highlight focuses on the latest advances in metal-free asymmetric oxidative C(sp3)–H bond functionalization using cooperative non-covalent organocatalysis.
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Organic Chemistry Frontiers
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