![4-[(2-{2-[2-(2-Aminoethoxy)ethoxy]ethoxy}ethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione structure](https://static.chemtradehub.com/structs/209/2093416-31-8-3162.webp "4-[(2-{2-[2-(2-Aminoethoxy)ethoxy]ethoxy}ethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione structure")
4-[(2-{2-[2-(2-Aminoethoxy)ethoxy]ethoxy}ethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
CAS Number:
2093416-31-8
Molecular Formula:
C21H28N4O7
Pd-catalyzed vinyl C–H amination with diaziridinone
Literature Information
Publication Date
2023-11-23
DOI
10.1039/D3QO01472J
Impact Factor
5.281
Authors
Jianjun Wang, Huiying Hong, Daguo Hu, Jieling Liu, Wei Liu, Yian Shi
View Original
Abstract
This work describes a Pd-catalyzed vinyl C–H amination of N-(quinolin-8-yl)acrylamides with di-t-butyldiaziridinone, providing ready access to a variety of 3-amino-N-(quinolin-8-yl)acrylamides. The reaction likely proceeds via vinyl C–H activation to form a pallada(II)cycle and subsequent amination with di-t-butyldiaziridinone.
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Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
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2-(7,7-Difluorobicyclo[4.1.0]hept-1-yl)ethanamine
CAS Number:
2098065-08-6
Molecular Formula:
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Molecular Formula:
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