(S)-(9H-Fluoren-9-yl)methyl (pyrrolidin-2-ylmethyl)carbamate hydrochloride
CAS Number:
1217813-15-4
Molecular Formula:
C20H23ClN2O2
Pulsed electrolysis: enhancing primary benzylic C(sp3)–H nucleophilic fluorination
Literature Information
Publication Date
2023-12-13
DOI
10.1039/D3QO01865B
Impact Factor
5.281
Authors
Alexander P. Atkins, Atul K. Chaturvedi, Joseph A. Tate, Alastair J. J. Lennox
View Original
Abstract
Electrosynthesis is an efficient and powerful tool for the generation of elusive reactive intermediates. The application of alternative electrolysis waveforms provides a new level of control for dynamic redox environments. Herein, we demonstrate that pulsed electrolysis provides a favourable environment for the generation and fluorination of highly unstable primary benzylic cations from C(sp3)–H bonds. By introduction of a toff period, we propose this waveform modulates the electrical double layer to improve mass transport and limit over-oxidation.
Recommended Journals
New Journal of Chemistry
Chemistry Education Research and Practice
Drug Discovery Today
Acta Materialia
Journal of Peptide Science
Organic Process Research & Development
Russian Journal of Applied Chemistry
Crystallography Reports
Russian Journal of Bioorganic Chemistry
Russian Journal of Coordination Chemistry
Related Literature
QM/MM calculation of protein magnetic shielding tensors with generalized hybrid-orbital method: A GIAO approach
Yoshinobu Akinaga, Jaewoon Jung, Seiichiro Ten-no
2011-07-15
Paper
DOI: 10.1039/C1CP21001G
Electrocatalytic oxygen evolution from water on a Mn(iii–v) dimer model catalyst—A DFT perspective
I. Panas
2011-07-20
Paper
DOI: 10.1039/C0CP02132F
A theoretical study of pure and mixed caesium clusters and cluster ions, CslHmO 0/+n, l ≤ 5: geometry, energetics and photofragmentation
Sebastian Krapf, Maria Schill, Sebastian Krötz, Thorsten Koslowski
2011-07-14
Paper
DOI: 10.1039/C1CP21274E
Experimental and theoretical study of the metastable decay of negatively charged nucleosides in the gas phase
Helga Dögg Flosadóttir, Hannes Jónsson, Snorri Th. Sigurdsson, Oddur Ingólfsson
2011-07-18
Paper
DOI: 10.1039/C1CP21298B
The role of disorder on the electronic structure of conjugated polymers. The case of poly-2,5-bis(phenylethynyl)-1,3,4-thiadiazole
J.M. Granadino-Roldán, M. Fernández-Gómez, Lin-Wang Wang
2011-07-08
Paper
DOI: 10.1039/C1CP20329K
Enhancement of hematoporphyrin IX potential for photodynamic therapy by entrapment in silica nanospheres
Paulo R. Silva, Lucas L. R. Vono, Breno P. Espósito, Maurício S. Baptista, Liane M. Rossi
2011-07-19
Paper
DOI: 10.1039/C1CP21525F
Synthesis of Ge-imogolite: influence of the hydrolysis ratio on the structure of the nanotubes
L. Olivi, C. Dominici, F. Ziarelli
2011-07-12
Paper
DOI: 10.1039/C1CP20346K
Double layer capacitance of anode/solid-electrolyte interfaces
2011-07-25
Paper
DOI: 10.1039/C1CP20508K
Nonequilibrium transport in quantum impurity models: exact path integral simulations
Dvira Segal, Andrew J. Millis, David R. Reichman
2011-06-15
Paper
DOI: 10.1039/C1CP20702D
You might also like
Compound Q&A
How should 2-Methylbenzene-1,4-diamine dihydrochloride (CAS: 615-45-2) be stored?
2-Methylbenzene-1,4-diamine dihydrochloride (CAS: 615-45-2) should be stored in ...
615-45-22-Methylbenzene-1,4-...
Compound Q&A
Is (1S,4S)-2,5-Diazabicyclo[2.2.1]heptane dihydrobromide (CAS: 132747-20-7) safe?
(1S,4S)-2,5-Diazabicyclo[2.2.1]heptane dihydrobromide is generally considered sa...
132747-20-7(1S,4S)-2,5-Diazabic...
Compound Q&A
What industries use (6-Chloropyridazin-3-YL)methanamine (CAS: 871826-15-2)?
(6-Chloropyridazin-3-YL)methanamine finds applications in the pharmaceutical ind...
871826-15-2(6-Chloropyridazin-3...
Compound Q&A
What are the main uses of 2-Fluoro-3-methylphenol (CAS: 77772-72-6)?
2-Fluoro-3-methylphenol is primarily used in the synthesis of pharmaceuticals, p...
77772-72-62-Fluoro-3-methylphe...
Compound Q&A
What precautions should be taken when handling 3-Methoxy-4-nitrobenzonitrile (CAS: 177476-75-4)?
When handling 3-Methoxy-4-nitrobenzonitrile, it is important to wear appropriate...
177476-75-43-Methoxy-4-nitroben...
Compound Q&A
What precautions should be taken when handling 1,3-Oxazolo[4,5-b]pyridine-2(3H)-thione (CAS: 211949-57-4)?
When handling 1,3-Oxazolo[4,5-b]pyridine-2(3H)-thione (CAS: 211949-57-4), it is ...
211949-57-4[1,3]Oxazolo[4,5-b]p...
Compound Q&A
What regulatory guidelines apply to 4-Ethynylbenzamide (CAS: 90347-86-7)?
4-Ethynylbenzamide (CAS: 90347-86-7) falls under various regulatory guidelines i...
90347-86-74-Ethynylbenzamide
Compound Q&A
What are the main uses of 3-(2-Ethylphenyl)-2-thioxo-4-imidazolidinone (CAS: 186822-57-1)?
3-(2-Ethylphenyl)-2-thioxo-4-imidazolidinone is primarily used as an intermediat...
186822-57-13-(2-Ethylphenyl)-2-...
Compound Q&A
What is (2-Fluoro-6-methoxyphenyl)acetic acid (CAS: 500912-19-6)?
(2-Fluoro-6-methoxyphenyl)acetic acid, also known as 4-fluoro-3-methoxybenzoic a...
500912-19-6(2-Fluoro-6-methoxyp...
Compound Q&A
What is the market or research trend for 2-[4-(Hydroxymethyl)phenoxy]ethanol (CAS: 102196-18-9)?
Market trends for 2-[4-(Hydroxymethyl)phenoxy]ethanol (CAS: 102196-18-9) indicat...
102196-18-92-[4-(Hydroxymethyl)...
Source Journal
Organic Chemistry Frontiers
CiteScore:
7.8
Self-citation Rate:
8.7%
Articles per Year:
724
Organic Chemistry Frontiers publishes high-quality research from across organic chemistry. Emphases are placed on studies that make significant contributions to the field of organic chemistry by reporting either new or significantly improved protocols or methodologies. Topics include, but are not limited to the following: Organic synthesis Development of synthetic methodologies Catalysis Natural products Functional organic materials Supramolecular and macromolecular chemistry Physical and computational organic chemistry
Recommended Compounds
N-(5-Fluoro-2-oxo-2,3-dihydro-4-pyrimidinyl)benzamide
CAS Number:
10357-07-0
Molecular Formula:
C11H8FN3O2
![2-Methyl-2-propanyl {3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-oxetanyl}carbamate structure](https://static.chemtradehub.com/structs/127/1279090-25-3-1b84.webp "2-Methyl-2-propanyl {3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-oxetanyl}carbamate structure")
2-Methyl-2-propanyl {3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-oxetanyl}carbamate
CAS Number:
1279090-25-3
Molecular Formula:
C20H30BNO5
![4-Chloro-2-{[(2-chlorophenoxy)acetyl]amino}benzoic acid structure](https://static.chemtradehub.com/structs/351/351424-20-9-9467.webp "4-Chloro-2-{[(2-chlorophenoxy)acetyl]amino}benzoic acid structure")
4-Chloro-2-{[(2-chlorophenoxy)acetyl]amino}benzoic acid
CAS Number:
351424-20-9
Molecular Formula:
C15H11Cl2NO4
Recommended Suppliers
Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.