2-Methyl-2-propanyl 4-iodo-1-piperidinecarboxylate
CAS Number:
301673-14-3
Molecular Formula:
C10H18INO2
Temperature-sensitive nanogels: poly(N-vinylcaprolactam) versus poly(N-isopropylacrylamide)
Literature Information
Publication Date
2011-12-16
DOI
10.1039/C2PY00485B
Impact Factor
5.582
Authors
Jose Ramos, Ainara Imaz, Jacqueline Forcada
View Original
Abstract
Poly(N-isopropylacrylamide) (PNIPAM) and poly(N-vinylcaprolactam) (PVCL) are temperature-responsive polymers which show a lower critical solution temperature (LCST) around 32 °C in aqueous solutions. Nanogels based on these temperature sensitive polymers swell at low temperatures and collapse at high ones, showing a volume phase transition temperature (VPTT) near physiological temperature. This unique behavior makes these nanogels attractive for biotechnological applications. PNIPAM is the building block of a huge amount of nanogels reported in the literature. However, PVCL is especially interesting due to the fact that it is very stable against hydrolysis and biocompatible. In this mini-review, various synthesis procedures together with the functionalization of different PNIPAM- and PVCL-based nanogels are revised and compared.
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Source Journal
Polymer Chemistry
CiteScore:
8.6
Self-citation Rate:
7.3%
Articles per Year:
457
Polymer Chemistry welcomes submissions in all areas of polymer science that have a strong focus on macromolecular chemistry. Manuscripts may cover a broad range of fields, yet no direct application focus is required.
Recommended Compounds
![2,2'-{2,2-Propanediylbis[(2,6-dibromo-4,1-phenylene)oxy]}diethanol structure](https://static.chemtradehub.com/structs/416/4162-45-2-b3d6.webp "2,2'-{2,2-Propanediylbis[(2,6-dibromo-4,1-phenylene)oxy]}diethanol structure")
2,2'-{2,2-Propanediylbis[(2,6-dibromo-4,1-phenylene)oxy]}diethanol
CAS Number:
4162-45-2
Molecular Formula:
C19H20Br4O4
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