N,N-dimethyl(piperidin-4-yl)methanamine hydrochloride
CAS Number:
172281-72-0
Molecular Formula:
C8H20Cl2N2
Au@SiO2 core–shell nanoparticles for laser desorption/ionization time of flight mass spectrometry
Literature Information
Publication Date
2012-03-13
DOI
10.1039/C2AN35074B
Impact Factor
4.616
Authors
Xiaoqing Zhu, Lianglan Wu, Divyesh C. Mungra, Sijing Xia, Jin Zhu
View Original
Abstract
In matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS), the analysis capability, especially for small molecules, is often compromised by the addition of organic matrices due to the existence of background signals. Herein we report a new detection method on the utility of core–shell nanoparticles (CSNPs) as energy transfer structure in LDI-TOF-MS. The LDI-TOF-MS based on gold–silica core–shell nanoparticles with ultrathin silica shell of 2–4 nm (Au@utSiO2 CSNPs) was effectively applied to the analysis of many compounds, especially for small functional molecules and polymers, which was more promising than MALDI-TOF-MS.
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Source Journal
Analyst
CiteScore:
7.8
Self-citation Rate:
5.6%
Articles per Year:
653
Analyst publishes analytical and bioanalytical research that reports premier fundamental discoveries and inventions, and the applications of those discoveries, unconfined by traditional discipline barriers.
Recommended Compounds
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[2-(Benzyloxy)-3-bromo-5-methylphenyl]boronic acid
CAS Number:
870777-20-1
Molecular Formula:
C14H14BBrO3
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Molecular Formula:
C24H21N6NaO5S
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