Diastereo- and enantioselective conjugate addition of α-substituted nitroacetates to maleimides under base-free neutral phase-transfer conditions‡

Literature Information

Publication Date 2011-08-25
DOI 10.1039/C1CC14043D
Impact Factor 6.222
Authors

Seiji Shirakawa, Shogo J. Terao, Rongjun He, Keiji Maruoka


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Abstract

Highly diastereo- and enantioselective conjugate addition of α-substituted nitroacetates to maleimides under base-free neutral phase-transfer conditions was developed for the synthesis of α,α-disubstituted α-amino acid derivatives.

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