Galantamine EP Impurity C (Dihydro Galantamine)

Basic Information

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CAS Number

21133-52-8

Molecular Formula

C17H23NO3

Molecular Weight

289.38 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Cryst.

Melting Point

122-124 ºC

Boiling Point

436.4°Cat760mmHg

Flash Point

217.7°C

Refractive Index

1.614

Specific Rotation

D27 -98° (alcohol)

SMILES

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CN1CCC23CCC(CC2OC4=C(C=CC(=C34)C1)OC)O

InChI

InChI=1S/C17H23NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-4,12,14,19H,5-10H2,1-2H3/t12-,14-,17-/m0/s1

InChIKey

GJRMHIXYLGOZSE-JDFRZJQESA-N

LogP

2.0743

Topological Polar Surface Area

41.93 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

404

Synonyms & References

English

CHEBI:543429
(-)-lycoramine
Dihydro Galantamine
AKOS040760538
CHEMBL469638
AC1L9F2N
W-201863
UNII-TAG8LU84K2
CHEBI:31789
GALANTAMINE HYDROBROMIDE IMPURITY C [EP IMPURITY]
21133-52-8
GALANTHAMINE, DIHYDRO-
GALANTHAMINE, 1,2-DIHYDRO-
DTXSID30175371
21133-52-8 (free base)
MS-24134
Lycoramine
LYCORAMINE [MI]
Dihydrogalanthamine
CS-0089534
6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-ol, 4a,5,7,8,9,10,11,12-octahydro-3-methoxy-11-methyl-, (4aS,6S,8aR)-
TAG8LU84K2
BDBM50278097
SCHEMBL1395930
SureCN1395930
1,2-Dihydrogalanthamine
Lycoramine free base
6H-BENZOFURO(3A,3,2-EF)(2)BENZAZEPIN-6-OL, 4A,5,7,8,9,10,11,12-OCTAHYDRO-3-METHOXY-11-METHYL-, (4AS,6S,8AR)-
(1R,12S,14S)-9-methoxy-4-methyl-11-oxa-4-azatetracyclo[8.6.1.0?,??.0?,??]heptadeca-6(17),7,9-trien-14-ol
Q27114686
Lycoramin

MDL Number

MFCD22683780

FAQ

What is Galantamine EP Impurity C (Dihydro Galantamine) (CAS: 21133-52-8)?

Galantamine EP Impurity C (Dihydro Galantamine) (CAS: 21133-52-8) is a compound derived from galantamine, a reversible acetylcholinesterase inhibitor. It has a chemical formula of C14H21NO4 and is often found as a by-product in the production of pharmaceutical grade galantamine. This impurity can affect the quality and efficacy of galantamine products.

What are the main uses of Galantamine EP Impurity C (Dihydro Galantamine) (CAS: 21133-52-8)?

Galantamine EP Impurity C (Dihydro Galantamine) (CAS: 21133-52-8) is primarily used in the pharmaceutical industry as a quality control and impurity monitoring compound. It is also used in research settings to study the effects of galantamine and its derivatives on acetylcholinesterase activity.

Is Galantamine EP Impurity C (Dihydro Galantamine) (CAS: 21133-52-8) safe?

Galantamine EP Impurity C (Dihydro Galantamine) (CAS: 21133-52-8) is generally considered safe when handled with appropriate precautions. It is not directly used in human consumption but as an impurity in drug formulations. Exposure to this impurity should be minimized, and proper protective measures such as gloves and safety goggles should be used during handling.

How should Galantamine EP Impurity C (Dihydro Galantamine) (CAS: 21133-52-8) be stored?

Galantamine EP Impurity C (Dihydro Galantamine) (CAS: 21133-52-8) should be stored in a cool, dry place away from direct sunlight and moisture. It is recommended to store it in a tightly sealed container to prevent degradation. The ideal storage temperature is between 15-25°C (59-77°F), and it should be protected from excessive humidity and light exposure to maintain its stability and purity.