Iridium-catalyzed enantioselective hydrogenation of vinyl boronates
Literature Information
Alexander Paptchikhine, Pradeep Cheruku, Mattias Engman, Pher G. Andersson
The first Ir-catalyzed asymmetric hydrogenations of vinyl boronates have been performed using low catalyst loadings (0.5 mol%) and pressure (as low as 1 bar). Good selectivities (76–98% ee) were obtained for a range of substrates.
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![(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-(methylselanyl)butanoic acid structure (2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-4-(methylselanyl)butanoic acid structure](https://static.chemtradehub.com/structs/121/1217852-49-7-f252.webp)



