Multiple convergence in polyketide biosynthesis: a third folding mode to the anthraquinonechrysophanol‡

Literature Information

Publication Date 2009-10-05
DOI 10.1039/B910501H
Impact Factor 6.222
Authors

Gerhard Bringmann, Tobias A. M. Gulder, Andreas Hamm, Michael Goodfellow, Hans-Peter Fiedler


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Abstract

The polyketidechrysophanol is shown to be formed, in an organism-specific way, by a third folding mode, involving a remarkable cyclization of a bicyclic diketo precursor, thus establishing the first example of multiple convergence in polyketide biosynthesis.

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