Efficient three-component one-pot synthesis of fully substituted pyridin-2(1H)-ones via tandem Knoevenagel condensation–ring-opening of cyclopropane–intramolecular cyclization

Literature Information

Publication Date 2009-05-13
DOI 10.1039/B905742K
Impact Factor 6.222
Authors

Fushun Liang, Xin Cheng, Jing Liu, Qun Liu


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Abstract

An efficient synthesis of fully substituted pyridin-2(1H)-ones was developed via three-component one-pot reactions of readily available 1-acetyl-1-carbamoyl cyclopropanes, malononitrile and cyclic secondary amines.

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