Synthesis and application of FePt/CNTs nanocomposite as a sensor and novel amideligand as a mediator for simultaneous determination of glutathione, nicotinamide adenine dinucleotide and tryptophan

Literature Information

Publication Date 2013-02-07
DOI 10.1039/C3CP00033H
Impact Factor 3.676
Authors

R. Moradi, S. A. Sebt, Roya Sadeghi, F. Karimi, A. Bahari, H. Arabi


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Abstract

In this study, we report the synthesis and application of a FePt/CNTs nanocomposite as a highly sensitive sensor and novel amide ligand (9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboximido)-4-ethylbenzene-1,2-diol as a mediator for the determination of glutathione (GSH), nicotinamide adenine dinucleotide (NADH) and tryptophan (Trp). The synthesized materials were characterized with different methods such as NMR, IR spectroscopy, TEM, XRD, FESEM, cyclic voltammetry, electrochemical impedance spectroscopy and square wave voltammetry (SWV). The modified electrode exhibited a potent and persistent electron mediating behavior followed by well-separated oxidation peaks of GSH, NADH and Trp. The peak currents were linearly dependent on GSH, NADH and Trp concentrations in the range of 0.08–220, 1.0–400 and 5.0–500 μmol L–1, with detection limits of 0.05, 0.8 and 1.0 μmol L–1, respectively. The modified electrode was used for the determination of these compounds in real samples.

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Physical Chemistry Chemical Physics

Physical Chemistry Chemical Physics
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