Chemically-selective surface glyco-functionalization of liposomes through Staudinger ligation

Literature Information

Publication Date 2009-04-28
DOI 10.1039/B822420J
Impact Factor 6.222
Authors

Hailong Zhang, Yong Ma, Xue-Long Sun


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Abstract

An efficient and chemoselective liposome surface glyco-functionalization method has been developed based on Staudinger ligation, in which the carbohydrate derivative carrying an azide spacer is conjugated onto the surface of preformed liposomes bearing a terminal triphosphine in PBSbuffer (pH 7.4) at room temperature.

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