Significant steroids: effective and general synthesis of 4α- and 4β-amino-5α-androstanes

Literature Information

Publication Date 2009-01-27
DOI 10.1039/B817910G
Impact Factor 6.222
Authors

Xianbing Ke, Hao Hu, Keda Zhang, Wenjin Xu, Qifeng Zhu, Lamei Wu, Xianming Hu


View Original

Abstract

4α-Aminosteroids were synthesized by the substitution of a 2α-bromo ketone using K2CO3 as an activator; 4β-aminosteroids were synthesized in excellent yields by a highly regioselective and trans-stereospecific ring opening of a steroidal 3,4α-epoxide using ZnCl2–H2O as a catalyst.

Related Literature

Back cover

Cover

DOI: 10.1039/D0SE90021D

Almond shell derived porous carbon for a high-performance anode of microbial fuel cells

Meizhen Li, Suqin Ci, Yichun Ding

2019-09-16 Paper

DOI: 10.1039/C9SE00659A

Mild and metal-free oxy- and amino-fluorination for the synthesis of fluorinated heterocycles

Dixit Parmar, Magnus Rueping

2014-09-26 Communication

DOI: 10.1039/C4CC05027D

A simple and green synthesis method for Ca-adamantanecarboxylate: a novel precursor for high temperature CO2 capture sorbent materials

G. V. Manohara, Mercedes Maroto-Valer, Susana Garcia

2019-10-15 Communication

DOI: 10.1039/C9SE00451C

Multicomponent decarboxylative allylations

Yamuna Ariyarathna, Jon A. Tunge

2014-09-25 Communication

DOI: 10.1039/C4CC07253G

A novel mesoporous carbon@silicon–silica nanostructure for high-performance Li-ion battery anodes

Chaohe Xu, Jianqiang Luo, Wei Wu, Jianlin Shi

2014-09-05 Communication

DOI: 10.1039/C4CC03545C

Ozone mediated depolymerization and solvolysis of technical lignins under ambient conditions in ethanol

M. B. Figueirêdo, H. J. Heeres, P. J. Deuss

2019-11-01 Paper

DOI: 10.1039/C9SE00740G

Sensitive detection of alkaline phosphatase by dephosphorylation-initiated transcription reaction-mediated dual signal amplification

Fei Ma, Wen-jing Liu, Li Liang, Bo Tang, Chun-Yang Zhang

2018-02-12 Communication

DOI: 10.1039/C8CC00540K

Highly enantioselective synthesis of trifluoromethyl cyclopropanes by using Ru(ii)–Pheox catalysts

Manato Kotozaki, Soda Chanthamath, Takuji Fujii, Kazutaka Shibatomi, Seiji Iwasa

2018-04-30 Communication

DOI: 10.1039/C8CC02286K

You might also like

Compound Q&A

What are the main uses of (5-Sulfamoyl-3-pyridinyl)boronic acid (CAS: 951233-61-7)?

(5-Sulfamoyl-3-pyridinyl)boronic acid is primarily used in chemical synthesis, p...

951233-61-7(5-Sulfamoyl-3-pyrid...
Compound Q&A

How is Benzyl 2-methyl-2-(methylsulfonyl)-4-pentenoate (CAS: 1942858-50-5) typically synthesized?

Benzyl 2-methyl-2-(methylsulfonyl)-4-pentenoate is typically synthesized via est...

1942858-50-5Benzyl 2-methyl-2-(m...
Compound Q&A

What precautions should be taken when handling 8-Fluoroquinolin-6-ol (CAS: 209353-22-0)?

When handling 8-Fluoroquinolin-6-ol (CAS: 209353-22-0), it is important to use p...

209353-22-08-Fluoroquinolin-6-o...
Compound Q&A

What are the physical and chemical properties of 1,3-Dibromo-5-(2-methyl-2-propanyl)benzene (CAS: 129316-09-2)?

1,3-Dibromo-5-(2-methyl-2-propanyl)benzene (CAS: 129316-09-2) is a crystalline c...

129316-09-21,3-Dibromo-5-(2-met...
Compound Q&A

What industries use Ethyl 7-chloro-4-oxo-1-(1,3-thiazol-2-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylate (CAS: 174726-87-5)?

Ethyl 7-chloro-4-oxo-1-(1,3-thiazol-2-yl)-1,4-dihydro-1,8-naphthyridine-3-carbox...

174726-87-5Ethyl 7-chloro-4-oxo...
Compound Q&A

What precautions should be taken when handling Delta-7-Avenasterol (CAS: 23290-26-8)?

When handling Delta-7-Avenasterol (CAS: 23290-26-8), it is important to wear app...

23290-26-8Delta-7-Avenasterol
872992-20-6N-({(5R)-3-[3-Fluoro...
Compound Q&A

What precautions should be taken when handling 2-Methyl-2-proanyl 4-[(2-aminophenyl)amino]-1-piperidinecarboxylate (CAS: 79099-00-6)?

When handling 2-Methyl-2-proanyl 4-[(2-aminophenyl)amino]-1-piperidinecarboxylat...

79099-00-62-Methyl-2-propanyl ...
Compound Q&A

What is N-Methyl-4-chlorobenzylamine hydrochloride (CAS: 65542-24-7)?

N-Methyl-4-chlorobenzylamine hydrochloride (CAS: 65542-24-7) is a organic compou...

65542-24-7N-Methyl-4-chloroben...
Compound Q&A

Is [2-(Dodecyloxy)ethoxy]acetic acid (CAS: 27306-90-7) safe?

[2-(Dodecyloxy)ethoxy]acetic acid (CAS: 27306-90-7) is generally considered safe...

27306-90-7[2-(Dodecyloxy)ethox...

Source Journal

Chemical Communications

Chemical Communications
CiteScore: 8.6
Self-citation Rate: 4.7%
Articles per Year: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.