Supramolecular aptamer–thrombin linear and branched nanostructures
Literature Information
Yossi Weizmann, Adam B. Braunschweig, Ofer I. Wilner, Zoya Cheglakov, Itamar Willner
α and β conjugated bis-aptamers against thrombin act as bidentate “glue” for the self-assembly of thrombin nanowires; mixing the bidentate aptamer with a tripodal tridentate α aptamer construct yields branched thrombin nanowire structures.
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![2,6-Bis({(2R)-2-[hydroxy(diphenyl)methyl]-1-pyrrolidinyl}methyl)-4-methylphenol structure 2,6-Bis({(2R)-2-[hydroxy(diphenyl)methyl]-1-pyrrolidinyl}methyl)-4-methylphenol structure](https://static.chemtradehub.com/structs/877/877395-58-9-70bf.webp)