Supramolecular aptamer–thrombin linear and branched nanostructures

Literature Information

Publication Date 2008-09-22
DOI 10.1039/B812486H
Impact Factor 6.222
Authors

Yossi Weizmann, Adam B. Braunschweig, Ofer I. Wilner, Zoya Cheglakov, Itamar Willner


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Abstract

α and β conjugated bis-aptamers against thrombin act as bidentate “glue” for the self-assembly of thrombin nanowires; mixing the bidentate aptamer with a tripodal tridentate α aptamer construct yields branched thrombin nanowire structures.

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