In vivo studies of a platinum(ii) metallointercalator

Literature Information

Publication Date 2008-09-26
DOI 10.1039/B811723C
Impact Factor 6.222
Authors

Dianne M. Fisher, Ronald R. Fenton, Janice R. Aldrich-Wright


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Abstract

An in vivo study for determining the toxicity and efficacy of [Pt(S,S-dach)(phen)Cl2路1.5H2O路0.5HCl (PHENSS) in female Specific Pathogen Free (SPF) Swiss nude mice bearing PC3 tumour xenografts revealed PHENSS to be non-toxic and effective in decreasing tumour growth.

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