Detection of mismatched DNAsvia the binding affinity of MutS using a gold nanoparticle-based competitive colorimetric method

Literature Information

Publication Date 2008-09-01
DOI 10.1039/B811346G
Impact Factor 6.222
Authors

Minseon Cho, Min Su Han, Changill Ban


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Abstract

A gold nanoparticle-based competitive colorimetric assay can detect mismatched DNAs using MutS, a mismatch binding protein, and determine their relative binding affinities for this protein by a simple color change and the melting temperature of DNA-functionalized nanoparticle assemblies.

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Contents list

2023-12-04 Front/Back Matter

DOI: 10.1039/D3NJ90182C

Front cover

2023-12-11 Cover

DOI: 10.1039/D3NJ90186F

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