Deprotonative cadmation of functionalized aromatics

Literature Information

Publication Date 2008-09-17
DOI 10.1039/B809543D
Impact Factor 6.222
Authors

Jean-Martial L’Helgoual’ch, Floris Chevallier, Mitsuhiro Yonehara, Masanobu Uchiyama, Aïcha Derdour, Florence Mongin


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Abstract

This communication describes the deproto-metalation of a large range of aromatics including heterocycles using a newly developed lithium–cadmium base; the reaction proceeds at room temperature with an excellent chemoselectivity and efficiency, and proved to be regioselective in most cases.

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