Copper-catalyzed three-component coupling of arynes, terminal alkynes and activated alkenes

Literature Information

Publication Date 2008-09-01
DOI 10.1039/B809409H
Impact Factor 6.222
Authors

Sivakolundu Bhuvaneswari, Masilamani Jeganmohan, Chien-Hong Cheng


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Abstract

The three-component coupling of benzynes with terminal alkynes and activated alkenes in the presence of CuI, PCy3 and CsF in a 1 : 1 mixture of CH3CN and THF at 50 °C for 5 h gave 1-alkyl-2-alkynylbenzenes in good to moderate yields.

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