Design of chiral bifunctional secondary amine catalysts for asymmetric enamine catalysis
Literature Information
Taichi Kano, Keiji Maruoka
A series of binaphthyl-based secondary amine catalysts containing various functional groups have been designed as new chiral bifunctional amine catalysts. These chiral organocatalysts have been successfully applied to several asymmetric reactions viaenamine intermediates and exhibit unique reactivity and selectivity in comparison with proline and its derivatives.
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