Design of chiral bifunctional secondary amine catalysts for asymmetric enamine catalysis

Literature Information

Publication Date 2008-09-10
DOI 10.1039/B809301F
Impact Factor 6.222
Authors

Taichi Kano, Keiji Maruoka


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Abstract

A series of binaphthyl-based secondary amine catalysts containing various functional groups have been designed as new chiral bifunctional amine catalysts. These chiral organocatalysts have been successfully applied to several asymmetric reactions viaenamine intermediates and exhibit unique reactivity and selectivity in comparison with proline and its derivatives.

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