Enantiomerically purebicyclo[3.3.1]nona-2,6-diene as the sole source of enantioselectivity in BIPHEP-Rh asymmetric hydrogenation
Literature Information
Tharmalingam Punniyamurthy, Monika Mayr, Alexander S. Dorofeev, Carole J. R. Bataille, Silvia Gosiewska, Bao Nguyen, Andrew R. Cowley, John M. Brown
In situ resolution of the rapidly racemising diphosphine BIPHEP and its relatives with the cationic Rh complex of (S,S)-bicyclonona-2,6-diene permits the asymmetric hydrogenation of dehydroamino esters.
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![Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, compd. with 1-pyrrolidineethanol (1:1) structure Benzeneacetic acid, 2-[(2,6-dichlorophenyl)amino]-, compd. with 1-pyrrolidineethanol (1:1) structure](https://static.chemtradehub.com/structs/119/119623-66-4-5301.webp)