4,5,6,7-Tetrahydro-2H-indazole

Basic Information

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CAS Number

2305-79-5

Molecular Formula

C7H10N2

Molecular Weight

122.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

83-85 °C

Boiling Point

140-142°C 2mm

Density

1.133

Flash Point

140-142°C/2mm

Refractive Index

1.573

SMILES

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C1CCC2=C(C1)C=NN2

InChI

InChI=1S/C7H10N2/c1-2-4-7-6(3-1)5-8-9-7/h5H,1-4H2,(H,8,9)

InChIKey

GDSQTWDUCDSZEY-UHFFFAOYSA-N

LogP

1.2885

Topological Polar Surface Area

28.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

103

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

15409-56-0
4,5,6,7-tetrahydro-2H-indazole
DMK7V56VG7
P10028
EN300-76433
4,6,7-Tetrahydroindazole
F3379-0301
AKOS002300437
MFCD00014565
4,5,6,7-Tetrahydroindazole
PB42174
3,4-Tetramethylenepyrazole
1H-Indazole,5,6,7-tetrahydro-
SY017712
SCHEMBL10509
FT-0617131
EINECS 218-977-9
4 5 6 7 Tetrahydroindazole
4,5,6,7-Tetrahydroindazole, 98%
J-014965
Z431947164
AKOS005143086
CHEMBL1817866
AS-50370
4,5,6,7-Tetrahydro-1H-indazole
4,6,7-Tetrahydro-1H-indazole
1H-Indazole,4,5,6,7-tetrahydro-
NSC-195333
4,5,6,7-tetrahydro-1H-indazol
AM85312
2305-79-5

MDL Number

MFCD00014565

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 4,5,6,7-Tetrahydro-2H-indazole (CAS: 2305-79-5)?

4,5,6,7-Tetrahydro-2H-indazole is a white or off-white crystalline solid. Its molecular weight is approximately 123.15 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. The compound is stable under normal conditions but reacts with strong bases and oxidizing agents. It has a low boiling point and is not highly reactive under normal storage conditions.

How is 4,5,6,7-Tetrahydro-2H-indazole (CAS: 2305-79-5) typically synthesized?

4,5,6,7-Tetrahydro-2H-indazole can be synthesized by the condensation of anhydrous ammonia with indole or by the reduction of indazole. Common methods include the von Braun indazole synthesis using anhydrous ammonia and indole, or catalytic hydrogenation of indazole. These methods yield the compound with good selectivity and moderate to high yields depending on the reaction conditions.

What industries use 4,5,6,7-Tetrahydro-2H-indazole (CAS: 2305-79-5)?

4,5,6,7-Tetrahydro-2H-indazole is widely used in the pharmaceutical industry for the synthesis of medicinal compounds. It is also utilized in the polymer industry for the development of various materials. Additionally, it has applications in the production of sensors and in semiconductor technology for its electronic properties.

What precautions should be taken when handling 4,5,6,7-Tetrahydro-2H-indazole (CAS: 2305-79-5)?

When handling 4,5,6,7-Tetrahydro-2H-indazole, it is crucial to use personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. Store it in a cool, well-ventilated area and avoid contact with strong bases and oxidizing agents. In case of spill, use appropriate spill cleanup procedures and ensure proper disposal. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.