Gold mediated glycosylations: selective activation of propargyl 1,2-orthoesters in the presence of aglycones containing a propargyl moiety

Literature Information

Publication Date 2008-07-21
DOI 10.1039/B806707D
Impact Factor 6.222
Authors

Gopalsamy Sureshkumar, Srinivas Hotha


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Abstract

Selective activation of propargyl 1,2-orthoesters in the presence of propargyl glycosides and propargyl ethers was studied; a catalytic amount of AuBr3 activated the propargyloxy group of the 1,2-orthoester thereby giving access to disaccharides with the propargyl group at the reducing end; furthermore, propargyl ethers were unaffected under the reaction conditions.

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