Palladium(ii)-catalyzed ring enlargement of 2-(arylmethylene)cyclopropylcarbinols: strong effect of substituent electronic nature on the reaction pathway

Literature Information

Publication Date 2008-05-08
DOI 10.1039/B804932G
Impact Factor 6.222
Authors

Guo-Qiang Tian, Zhi-Liang Yuan, Zhi-Bin Zhu


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Abstract

In the presence of Pd(II) catalyst and copper(II) bromide, 2-(arylmethylene)cyclopropylcarbinols undergo ring enlargement to deliver (arylcyclobutenyl)carbinols or hydrogenated furans in good yields under mild conditions; mechanisms accounting for the distinct products have been proposed on the basis of control and deuterium labeling experiments.

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