Chiral tertiary 2-furyl alcohols: diversified key intermediates to bioactive compounds. Their enantioselective synthesis via (2-furyl)aluminium addition to ketones catalyzed by a titanium catalyst of (S)-BINOL

Literature Information

Publication Date 2008-04-17
DOI 10.1039/B802441C
Impact Factor 6.222
Authors

Kuo-Hui Wu, Da-Wei Chuang, Chien-An Chen, Han-Mou Gau


View Original

Abstract

Novel asymmetric 2-furyl additions of (2-furyl)AlEt2(THF) to aromatic ketones and one α,β-unsaturated ketone catalyzed by a titanium catalyst of 10–20 mol% (S)-BINOL are reported to furnish tertiary furyl alcohols in good to excellent enantioselectivities of 87–93% ee.

Related Literature

Template-free synthesis of 3D Nb3O7F hierarchical nanostructures and enhanced photocatalytic activities

Zheng Wang, Jungang Hou, Chao Yang, Shuqiang Jiao, Kai Huang, Hongmin Zhu

2013-01-24 Paper

DOI: 10.1039/C2CP44326K

High-precision measurement-based correlation studies among atomic force microscopy, Rayleigh scattering, and surface-enhanced Raman scattering at the single-molecule level

Hae Mi Lee, Jung-Hoon Lee, Hyung Min Kim, Seung Min Jin, Hyo Sun Park, Jwa-Min Nam, Yung Doug Suh

2013-01-08 Paper

DOI: 10.1039/C3CP43817A

Inside front cover

Cover

DOI: 10.1039/C3CP90027D

2nd TYC workshop on energy materials

F. Baletto, J. Blumberger, A. Shluger

2013-02-20 Editorial

DOI: 10.1039/C2CP90214A

Molecular sentinel-on-chip for SERS-based biosensing

Anuj Dhawan, Yan Du, Dale Batchelor, Donovan N. Leonard, Veena Misra

2013-02-20 Paper

DOI: 10.1039/C3CP00076A

Quantum yields for the photolysis of glyoxal below 350 nm and parameterisations for its photolysis rate in the troposphere

Robert J. Salter, Mark A. Blitz, Dwayne E. Heard, Tamás Kovács, Michael J. Pilling, Andrew R. Rickard, Paul W. Seakins

2013-01-31 Paper

DOI: 10.1039/C3CP43597K

Giant reduction of the phase transition temperature for beryllium doped VO2

Jiajia Zhang, Haiyan He, Yi Xie

2013-02-01 Paper

DOI: 10.1039/C3CP44476G

Measurement of the localised plasmon penetration depth for gold nanoparticles using a non-invasive bio-stacking method

Thomas Read, Rouslan V. Olkhov, Andrew M. Shaw

2013-03-08 Paper

DOI: 10.1039/C3CP50758K

Oxidation of carbon monoxide, hydrogen peroxide and water at a boron doped diamond electrode: the competition for hydroxyl radicals

Ana Stefanova, Siegfried Ernst, Helmut Baltruschat

2013-01-29 Paper

DOI: 10.1039/C3CP44643C

Persistent misconceptions regarding SERS

2012-12-21 Perspective

DOI: 10.1039/C2CP44030J

You might also like

Compound Q&A

How should waste containing (6-Bromo-2-naphthyl)oxy](dimethyl)(2-methyl-2-propanyl)silane be handled?

Waste containing (6-Bromo-2-naphthyl)oxy](dimethyl)(2-methyl-2-propanyl)silane (...

100751-65-3[(6-Bromo-2-naphthyl...
Compound Q&A

How is 7-Fluoro-4-isoquinolinecarboxylic acid (CAS: 1841081-40-0) typically synthesized?

7-Fluoro-4-isoquinolinecarboxylic acid can be synthesized via a multi-step proce...

1841081-40-07-Fluoro-4-isoquinol...
Compound Q&A

What are the physical and chemical properties of 2,3,5,6-Tetrabromothieno[3,2-b]thiophene (CAS: 124638-53-5)?

2,3,5,6-Tetrabromothieno[3,2-b]thiophene is a crystalline compound with a high m...

124638-53-52,3,5,6-Tetrabromoth...
Compound Q&A

Is 1-[4-(Benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide (CAS: 1542705-92-9) safe?

1-[4-(Benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indol...

1542705-92-91-[4-(Benzylamino)-7...
Compound Q&A

What is the market or research trend for imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylic acid, 3,4-dihydro-3-methyl-4-oxo- (CAS: 113942-30-6)?

The market for imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylic acid, 3,4-dihydro-3...

113942-30-6Imidazo[5,1-d]-1,2,3...
Compound Q&A

What is 3-(Triisopropylsilyl)propiolaldehyde (CAS: 163271-80-5)?

3-(Triisopropylsilyl)propiolaldehyde is a synthetic organic compound with the CA...

163271-80-53-(Triisopropylsilyl...
Compound Q&A

What regulatory guidelines apply to 6-Nitro-2H-1,4-benzoxazin-3(4H)-one (CAS: 81721-87-1)?

6-Nitro-2H-1,4-benzoxazin-3(4H)-one (CAS: 81721-87-1) is subject to various regu...

81721-87-16-Nitro-2H-1,4-benzo...
Compound Q&A

How should waste containing (3-Fluorophenyl)(4-{[(2-methyl-2-propanyl)oxy]carbonyl}-1-piperazinyl)acetic acid (CAS: 885272-91-3) be handled?

Waste containing (3-Fluorophenyl)(4-{[(2-methyl-2-propanyl)oxy]carbonyl}-1-piper...

885272-91-3(3-Fluorophenyl)(4-{...
Compound Q&A

What are the physical and chemical properties of N,N'-4,4'-Biphenyldiyldiisonicotinamide (CAS: 55119-40-9)?

N,N'-4,4'-Biphenyldiyldiisonicotinamide is a white crystalline solid with a mole...

55119-40-9N,N'-4,4'-Biphenyldi...
Compound Q&A

What industries use 6-Bromo-8-fluoro-2-quinazolinol (CAS: 1036756-15-6)?

6-Bromo-8-fluoro-2-quinazolinol is primarily used in the pharmaceutical industry...

1036756-15-66-Bromo-8-fluoro-2-q...

Source Journal

Chemical Communications

Chemical Communications
CiteScore: 8.6
Self-citation Rate: 4.7%
Articles per Year: 2458

ChemComm publishes urgent research which is of outstanding significance and interest to experts in the field, while also appealing to the journal’s broad chemistry readership. Our communication format is ideally suited to short, urgent studies that are of such importance that they require accelerated publication. Our scope covers all topics in chemistry, and research at the interface of chemistry and other disciplines (such as materials science, nanoscience, physics, engineering and biology) where there is a significant novelty in the chemistry aspects. Major topic areas covered include: Analytical Chemistry Catalysis Chemical Biology and medicinal chemistry Computational Chemistry and Machine Learning Energy and sustainable chemistry Environmental Chemistry Green Chemistry Inorganic Chemistry Materials Chemistry Nanoscience Organic Chemistry Physical Chemistry Polymer Chemistry Supramolecular Chemistry

Recommended Compounds

Recommended Suppliers

Disclaimer
This page provides academic journal information for reference and research purposes only. We are not affiliated with any journal publishers and do not handle publication submissions. For publication-related inquiries, please contact the respective journal publishers directly.
If you notice any inaccuracies in the information displayed, please contact us at support@chemtradehub.com. We will promptly review and address your concerns.