A concise organocatalytic and enantioselective synthesis of isotetronic acids

Literature Information

Publication Date 2007-09-10
DOI 10.1039/B711192D
Impact Factor 6.222
Authors

Jean-Marc Vincent, Chrystèle Margottin, Muriel Berlande, Dominique Cavagnat, Thierry Buffeteau, Yannick Landais


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Abstract

A concise enantioselective route to isotetronic acids using an organocatalyzed aldol reaction between α-oxocarboxylic acids and aldehydes has been developed, leading to the titled compounds in reasonable yields and good enantioselectivities.

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