The relationships between oxidase and synthase activities of flavin dependent thymidylate synthase (FDTS)

Literature Information

Publication Date 2007-04-25
DOI 10.1039/B700977A
Impact Factor 6.222
Authors

Anatoly Chernyshev, Todd Fleischmann, Eric M. Koehn, Scott A. Lesley, Amnon Kohen


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Abstract

New findings lead to a revised understanding of the substrates' binding order, the role of the substrate as an activator, and the observed lag phase in the FDTS catalyzed reaction.

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