Synthesis of para-methoxybenzyl (PMB) ethers under neutral conditions

Literature Information

Publication Date 2007-02-26
DOI 10.1039/B617926F
Impact Factor 6.222
Authors

Ernest O. Nwoye, Gregory B. Dudley


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Abstract

2-(4-Methoxybenzyloxy)-4-methylquinoline reacts with methyl triflate in the presence of alcohols to generate a neutral organic salt that transfers the para-methoxybenzyl (PMB) protecting group onto alcohols in high yield and under mild conditions.

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