Enzyme stabilizer DTT catalyzes nitrilase analogue hydrolysis of nitriles

Literature Information

Publication Date 2006-02-10
DOI 10.1039/B516937B
Impact Factor 6.222
Authors

Margit Winkler, Anton Glieder, Norbert Klempier


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Abstract

Amides are the dominating products in some nitrilase catalyzed conversions of α-activated nitriles, but unexpectedly this hydrolytic reaction is also catalyzed by 1,4-dithio-DL-threitol (DTT), a standard antioxidizing enzyme stabilizer.

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