Design and synthesis of artificial phospholipid for selective cleavage of integral membrane protein

Literature Information

Publication Date 2005-08-17
DOI 10.1039/B507917A
Impact Factor 6.222
Authors

Takumi Furuta, Minatsu Sakai, Hiroyasu Hayashi, Tomohiro Asakawa, Fumi Kataoka, Satoshi Fujii, Takashi Suzuki, Yasuo Suzuki, Kiyoshi Tanaka, Nathan Fishkin, Koji Nakanishi


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Abstract

An artificial phospholipid, possessing saturated alkyl chains as a membrane anchor and protein recognition site as well as an Fe(III)–EDTA moiety as a protein cleavable polar head group, was designed and synthesized based on the amidite method for the purpose of examination of cleavage of integral membrane proteins.

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