Design and synthesis of artificial phospholipid for selective cleavage of integral membrane protein
Literature Information
Takumi Furuta, Minatsu Sakai, Hiroyasu Hayashi, Tomohiro Asakawa, Fumi Kataoka, Satoshi Fujii, Takashi Suzuki, Yasuo Suzuki, Kiyoshi Tanaka, Nathan Fishkin, Koji Nakanishi
An artificial phospholipid, possessing saturated alkyl chains as a membrane anchor and protein recognition site as well as an Fe(III)–EDTA moiety as a protein cleavable polar head group, was designed and synthesized based on the amidite method for the purpose of examination of cleavage of integral membrane proteins.
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