A remarkably effective catalyst for the asymmetric transfer hydrogenation of aromatic ketones in water and air

Literature Information

Publication Date 2005-07-29
DOI 10.1039/B507276J
Impact Factor 6.222
Authors

Xiaofeng Wu, Daniele Vinci, Takao Ikariya, Jiangliang Xiao


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Abstract

A Rh(III) complex generated in situ from [Cp*RhCl2]2 and (1R,2R)-N-(p-toluenesulfonyl)-1,2-cyclohexanediamine (TsCYDN) serves as a remarkably effective, robust catalyst for the asymmetric transfer hydrogenation of aromatic ketones by HCOONa in water in air, affording alcohols in up to 99% ee.

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