Comb-shaped poly(ethylene glycol)-modified subtilisin Carlsberg is soluble and highly active in ionic liquids

Literature Information

Publication Date 2005-08-02
DOI 10.1039/B505479F
Impact Factor 6.222
Authors

Kazunori Nakashima, Tatsuo Maruyama, Noriho Kamiya, Masahiro Goto


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Abstract

Subtilisin Carlsberg conjugated with comb-shaped poly(ethylene glycol) was solubilized in common ionic liquids without adding water, and exhibited higher transesterification activity in an ionic liquid, [Emim][Tf2N], than in organic solvents commonly used for enzymatic biotransformation.

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Chemical Communications

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