Photoinduced DNA end capping viaN3-methyl-5-cyanovinyl-2′-deoxyuridine

Literature Information

Publication Date 2005-05-24
DOI 10.1039/B504162G
Impact Factor 6.222
Authors

Yoshinaga Yoshimura, Tadayoshi Ikemoto, Akio Nakazawa, Masayuki Hayashi, Isao Saito


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Abstract

A modified oligodeoxynucleotide (ODN) containing N3-methyl-5-cyanovinyl-2′-deoxyuridine reacts by photoirradiation at 366 nm with an adenine residue of a complementary template ODN to yield an end-capped ODN in 87% yield.

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