Noncatalytic mono-N-methylation of aniline in supercritical methanol: the kinetics and acid/base effect
Literature Information
Yoshihiro Takebayashi, Yoshinori Morita, Hideki Sakai, Masahiko Abe, Satoshi Yoda, Takeshi Furuya, Tsutomu Sugeta, Katsuto Otake
Aniline is easily N-methylated in supercritical methanol without catalyst at 350 °C and 0.237 g cm−3 to give mono-N-methylaniline with high selectivity, and the reaction rate is increased by a small amount of base (LiOH, NaOH, KOH, and CH3ONa), indicating a difference in the reaction mechanism from the ordinary acid-catalyzed one.
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