Continuous synthesis of aminophenols from nitroaromatic compounds by combination of metal and biocatalyst
Literature Information
Heather R. Luckarift, Lloyd J. Nadeau, Jim C. Spain
The combined action of immobilized hydroxylaminobenzene mutase and zinc in a flow-through system catalyzes the conversion of nitroaromatic compounds to the corresponding ortho-aminophenols, including a novel analog of chloramphenicol.
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![5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]chromen-4-one structure 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]chromen-4-one structure](https://static.chemtradehub.com/structs/191/1914963-20-4-2b05.webp)
