Notable deuterium effect on the electron transfer rate of myoglobin

Literature Information

Publication Date 2004-11-17
DOI 10.1039/B413100B
Impact Factor 6.222
Authors

Yasuhiro Mie, Chiho Yamada, Tadayuki Uno, Saburo Neya, Fumio Mizutani, Katsuhiko Nishiyama, Isao Taniguchi


View Original

Abstract

The electron transfer reaction of wild-type myoglobin at an electrode was significantly facilitated in a D2O buffer as compared with that in an H2O buffer, with k0′H2O/k0′D2O = 0.13, while a minimal deuterium kinetic isotope effect on the myoglobin with modification at distal histidine (His-64) was observed.

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