Probing DNA selectivity of ruthenium metallointercalators using ESI mass spectrometry
Literature Information
Jennifer L. Beck, Rajesh Gupta, Thitima Urathamakul, Nyree L. Williamson, Margaret M. Sheil, Janice R. Aldrich-Wright, Stephen F. Ralph
ESI mass spectra show that up to five ruthenium molecules can bind non-covalently to double stranded 16mer DNA, and provide information on the relative affinity and DNA sequence selectivity of different ruthenium complexes.
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![5-Acetyl-2,3-dihydrobenzo[b]furan structure 5-Acetyl-2,3-dihydrobenzo[b]furan structure](https://static.chemtradehub.com/structs/908/90843-31-5-eea4.webp)

