Probing DNA selectivity of ruthenium metallointercalators using ESI mass spectrometry

Literature Information

Publication Date 2003-02-10
DOI 10.1039/B212132H
Impact Factor 6.222
Authors

Jennifer L. Beck, Rajesh Gupta, Thitima Urathamakul, Nyree L. Williamson, Margaret M. Sheil, Janice R. Aldrich-Wright, Stephen F. Ralph


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Abstract

ESI mass spectra show that up to five ruthenium molecules can bind non-covalently to double stranded 16mer DNA, and provide information on the relative affinity and DNA sequence selectivity of different ruthenium complexes.

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