Conformational studies on phenyl thioglycosides: a remote effect on disaccharide linkage by phenyl aglycons attenuates recognition of galabiosides by a bacterial adhesin

Literature Information

Publication Date 2003-01-14
DOI 10.1039/B210649C
Impact Factor 6.222
Authors

Jörgen Ohlsson, Anders Sundin, Ulf J. Nilsson


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Abstract

Phenyl S-galabiosides display altered conformational properties, as compared to phenyl O-galabiosides, characterised by a remote effect on the galabiose intersaccharidic glycoside bond by the phenyl aglycon, resulting in significantly lowered affinity for the PapG class II adhesin of uropathogenic E. coli.

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