Non-steady-state kinetic study of the SN2 reaction between p-nitrophenoxide ion and methyl iodide in aprotic solvents containing water. Evidence for a 2-step mechanism

Literature Information

Publication Date 2002-11-08
DOI 10.1039/B208635B
Impact Factor 3.876
Authors

Yun Lu, Kishan L. Handoo, Vernon D. Parker


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Abstract

Non-steady-state kinetic studies reveal that the SN2 reaction between p-nitrophenoxide ion and methyl iodide in acetonitrile containing water follows a 2-step mechanism involving the formation of a kinetically significant intermediate.

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Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry
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Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

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