1-{2-[(7-Chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate (1:1) | CAS No. 99592-39-9
1-{2-[(7-Chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate (1:1)
Basic Information
CAS Number
99592-39-9
Molecular Formula
C20H16Cl3N3O4S
Molecular Weight
500.8 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
158-165°C
Solubility
DMSO: soluble20mg/mL, clear
Safety Information
View Safety InformationHazard Statement
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- SERTACONAZOLE NITRATE (MART.)
- racemic sertaconazole nitrate
- Tox21_110718
- Onabet
- Ertaczo (TN)
- 1-[2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole; nitric acid
- Sertaconazole mononitrate
- SERTACONAZOLE NITRATE [EP MONOGRAPH]
- Dermofix
- 1-[2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole;nitric acid
- CCG-221045
- FI-7045
- FI-7056
- 1-[2-[(7-Chloro-1-benzothien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate
- 1H-IMIDAZOLE, 1-(2-((7-CHLOROBENZO(B)THIEN-3-YL)METHOXY)-2-(2,4-DICHLOROPHENYL)ETHYL)-, NITRATE (1:1)
- F20635
- Sertaconazolenitrate
- BCP09311
- AKOS015888158
- 1DV05410M5
- SERTACONAZOLE NITRATE (EP MONOGRAPH)
- AMY32537
- 1-[2-[(7-chloranyl-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole; nitric acid
- SERTACONAZOLE NITRATE [WHO-DD]
- MLS002154122
- DTXSID2045529
- UNII-1DV05410M5
- AC-739
- SERTACONAZOLE NITRATE [ORANGE BOOK]
- rac-1-(2-((7-chloro-1-benzothiophen-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate
- CHEMBL1200725
MDL Number
MFCD00918063
Customs Code
2934999090
FAQ
What are the physical and chemical properties of 1-{2-[(7-Chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate (CAS: 99592-39-9)?
The compound is a crystalline solid with a molecular weight of approximately 719.85 g/mol. It has a high solubility in organic solvents such as DMSO and DMF. Chemically, it is stable under normal conditions but can react with strong bases. The nitrate salt form enhances its stability and reactivity in certain applications.
How is 1-{2-[(7-Chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate (CAS: 99592-39-9) typically synthesized?
This compound is synthesized through a multi-step process involving condensation reactions and nitration. Commonly, it involves reacting 7-chloro-1-benzothiophen-3-yl methanol with 2-(2,4-dichlorophenyl)ethyl isocyanate to form the imidazole, followed by nitration to add the nitrate group. The process requires careful control of reaction conditions to ensure high yield and selectivity.
What industries use 1-{2-[(7-Chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate (CAS: 99592-39-9)?
This compound is primarily used in the pharmaceutical industry for developing new drugs. It also finds applications in the synthesis of novel materials, particularly in the areas of polymer chemistry and sensor technology. Due to its specific chemical structure, it can be used in the production of semiconductors and other advanced technologies.
What precautions should be taken when handling 1-{2-[(7-Chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate (CAS: 99592-39-9)?
Handling this compound requires appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. It should be conducted in a well-ventilated area or under a fume hood to minimize exposure to vapors. Proper containment and disposal methods should be followed as per the Material Safety Data Sheet (MSDS/SDS).
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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