N,1-Bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidine

Basic Information

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CAS Number

98929-98-7

Molecular Formula

C36H29N3O6

Molecular Weight

599.64 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

159-161°C

Specific Rotation

-4.5° - -6.5° (c=1, DMF)

SMILES

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C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CN(C=N4)C(=O)OCC5C6=CC=CC=C6C7=CC=CC=C57)C(=O)O

InChI

InChI=1S/C36H29N3O6/c40-34(41)33(38-35(42)44-19-31-27-13-5-1-9-23(27)24-10-2-6-14-28(24)31)17-22-18-39(21-37-22)36(43)45-20-32-29-15-7-3-11-25(29)26-12-4-8-16-30(26)32/h1-16,18,21,31-33H,17,19-20H2,(H,38,42)(H,40,41)/t33-/m0/s1

InChIKey

WTBXFPFCUZKREB-XIFFEERXSA-N

LogP

6.214700000000006

Topological Polar Surface Area

119.75 Å²

Hydrogen Bond Donor/Acceptor

2 / 9

Complexity

1030

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

S-98929-98-7
AM81821
SCHEMBL1486207
N,N'-Bis(9-fluorenylmethyloxycarbonyl)-L-histidine
Fmoc-His(Fmoc)
Fmoc-His(Fmoc)-OH
A,N-im-di-Fmoc-L-histidine
(S)-3-(1-(((9H-fluoren-9-yl)methoxy)carbonyl)-1H-imidazol-4-yl)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)propanoic acid
N,1-Bis{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-histidine
AS-14330
98929-98-7
HY-W013083
DTXSID50662435
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-(9H-fluoren-9-ylmethoxycarbonyl)imidazol-4-yl]propanoic acid
L-Histidine, N,1-bis[(9H-fluoren-9-ylmethoxy)carbonyl]-
WTBXFPFCUZKREB-XIFFEERXSA-N
CS-W013799
(S)-3-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-1H-imidazol-4-yl)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid
FD21667
N,N'-Bis(9-fluorenylmethyloxycarbonyl)-L-histidine (Fmoc-L-His(Fmoc)-OH)
MFCD00070658
N-
N,1-Bis-Fmoc-L-histidine
Na,Nt-Bis(((9H-fluoren-9-yl)methoxy)carbonyl)-L-histidine
AKOS015922833
M03416
Fmoc-L-His(Fmoc)-OH

MDL Number

MFCD00070658

FAQ

What is N,1-Bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidine (CAS: 98929-98-7)?

N,1-Bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidine is an organic compound with a molecular structure derived from histidine and 9H-fluorene. It features a histidine backbone with fluorene derivatives attached, exhibiting unique chemical properties suitable for various applications. The compound is characterized by its stability and potential use in pharmaceutical and research settings.

What are the main uses of N,1-Bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidine (CAS: 98929-98-7)?

N,1-Bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidine is primarily used in pharmaceutical research for the development of new drugs, particularly in the synthesis of peptides and proteins. It also finds applications in organic synthesis and as a protective group in research settings.

Is N,1-Bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidine (CAS: 98929-98-7) safe?

N,1-Bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidine is considered safe for laboratory use when proper precautions are taken. It is important to handle the compound with gloves and to avoid inhalation or contact with eyes and skin. Ensure proper ventilation and store in a cool, dry place away from direct sunlight.

How should N,1-Bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidine (CAS: 98929-98-7) be stored?

N,1-Bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidine should be stored in a cool, dry place to maintain its stability. It should be kept away from direct sunlight and sources of heat. The compound should be stored in a tightly sealed container to prevent contamination and degradation. Proper storage conditions are essential to ensure the compound remains effective for its intended use.