5-Isopropyl-2-pyrimidinamine

Basic Information

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CAS Number

98432-17-8

Molecular Formula

C7H11N3

Molecular Weight

137.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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CC(C)C1=CN=C(N=C1)N

InChI

InChI=1S/C7H11N3/c1-5(2)6-3-9-7(8)10-4-6/h3-5H,1-2H3,(H2,8,9,10)

InChIKey

YKVWHWNSINXNPF-UHFFFAOYSA-N

LogP

1.1822000000000001

Topological Polar Surface Area

51.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

Synonyms & References

English

SCHEMBL84396
5-isopropylpyrimidin-2-amine
AS-49307
5-propan-2-ylpyrimidin-2-amine
5-(Propan-2-yl)pyrimidin-2-amine
FD7250
98432-17-8
DTXSID40609955
5-Isopropyl-2-pyrimidinamine
GS2574
AMY15293
AKOS012857231
YDA43217
EN300-1663614
Z1137168328
FT-0649533
MFCD08460249
CS-0210152
SB56689
5-(1-Methylethyl)-2-pyrimidinamine
5-isopropyl pyrimidin-2-amine
PYRIMIDINE,2-AMINO-5-ISOPROPYL
2-Amino-5-isopropyl-pyrimidin
2-Pyrimidinamine,5-isopropyl
5-isopropyl-pyrimidin-2-ylamine
5-(propan-2-yl)pyrimidin-2-amine

MDL Number

MFCD08460249

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 5-Isopropyl-2-pyrimidinamine (CAS: 98432-17-8)?

5-Isopropyl-2-pyrimidinamine is a crystalline solid with a molecular weight of approximately 171.24 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. This compound is relatively stable but can undergo hydrolysis in basic conditions. It is an important intermediate in the synthesis of various pharmaceuticals and agrochemicals.

How is 5-Isopropyl-2-pyrimidinamine (CAS: 98432-17-8) typically synthesized?

5-Isopropyl-2-pyrimidinamine is typically synthesized via the reaction of 2-bromopyrimidine with isopropylamine in the presence of a base like potassium carbonate. The reaction is conducted in an organic solvent such as dimethylformamide (DMF). The yield is generally good, and the reaction can be performed under mild conditions.

What industries use 5-Isopropyl-2-pyrimidinamine (CAS: 98432-17-8)?

5-Isopropyl-2-pyrimidinamine is primarily used in the pharmaceutical and agrochemical industries as a precursor to various drugs and pesticides. It is also utilized in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 5-Isopropyl-2-pyrimidinamine (CAS: 98432-17-8)?

When handling 5-Isopropyl-2-pyrimidinamine, it is essential to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from sources of heat and moisture. In case of a spill, it should be handled using appropriate spill cleanup procedures, and the Material Safety Data Sheet (MSDS) should be consulted for further guidance. Fume hoods should be used during synthesis to minimize exposure to fumes.