5-Oxo-L-proline

Basic Information

View in Editor

CAS Number

98-79-3

Molecular Formula

C5H7NO3

Molecular Weight

129.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

155-162 °C<br />160-163 °C

Boiling Point

239.15°C (rough estimate)

Density

1.3816 (rough estimate)

Water Solubility

10-15 g/100 mL (20 ºC)

Flash Point

227.8 °C

Solubility

H2O: 1 M at 20 °C, clear, colorless

Refractive Index

-10 ° (C=5, H2O)

Specific Rotation

-27.5 º (c=10, 1 N NaOH)

SMILES

View in Editor

OC(=O)[C@@H]1CCC(=O)N1

InChI

InChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1

InChIKey

ODHCTXKNWHHXJC-VKHMYHEASA-N

LogP

-0.6504000000000001

pKa

3.32(at 25℃)

Topological Polar Surface Area

66.39999999999999 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

154

Safety Information

View Safety Information

GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Stability

Stable. Incompatible with bases, acids, strong oxidizing agents.

Synonyms & References

English

(S)-5-Oxopyrrolidine-2-carboxylic acid
pidolic acid
glutiminic acid
5-oxoproline
Pyr-OH
L-Pyroglutamic acid
H-Pyr-OH
L-2-Pyrrolidone-5-carboxylic acid
(S)-(-)-2-Pyrrolidinone-5-carboxylic acid
L-Pyrpglutamic Acid
5-Oxopyrrolidine-2-carboxylic acid
5-Pyrrolidone-2-carboxylic acid
L-5-Pyrrolidone-2-carboxylic acid
pyroglutamic acid
Pyrrolidonecarboxylic Acid
(S)-(-)-2-Pyrrolidone-5
5 oxoproline
GlutaMic acid lactaM
GlutiMic acid
hydroxy-pyridin-3-yl-acetic acid
L-5-Oxo-2-pyrrolidine carboxylic acid
L-GlutiMinic acid
α- AMinoglutaric acid lactaM
L-Glutamic Acid Lactam
(S)-2-Pyrrolidone-5-carboxylic Acid
(S)-(-)-2-Pyrrolidone-5-carboxylic acid
5-oxo-L-proline
(2S)-5-oxopyrrolidine-2-carboxylic acid
L-5-Oxoproline
L-Proline, 5-oxo-
Pyroglutamate

MDL Number

MFCD00005272

Customs Code

2933790090

FAQ

What is 5-Oxo-L-proline (CAS: 98-79-3)?

5-Oxo-L-proline, with the CAS number 98-79-3, is a cyclic amino acid derivative. It has the chemical formula C4H6N2O3 and is known for its stability in various chemical environments. This compound is commonly used in biochemical research and has a distinctive structure that makes it a key intermediate in the synthesis of other compounds.

What are the main uses of 5-Oxo-L-proline (CAS: 98-79-3)?

5-Oxo-L-proline is primarily used in pharmaceutical research for the development of drugs and as a precursor in the synthesis of amino acids and related compounds. It also finds applications in the food industry and industrial chemical processes due to its functional properties. Its role in biochemical pathways makes it valuable for research in metabolism and biochemistry.

Is 5-Oxo-L-proline (CAS: 98-79-3) safe?

5-Oxo-L-proline is generally considered safe when handled properly. However, it is important to follow standard safety protocols, especially when working with concentrated solutions. Protective measures such as gloves and safety goggles are recommended, and it should be stored away from incompatible materials to ensure safety in laboratory and industrial settings.

How should 5-Oxo-L-proline (CAS: 98-79-3) be stored?

5-Oxo-L-proline should be stored in a cool, dry place, away from direct light. It is typically kept in airtight containers to prevent moisture absorption. The optimal storage temperature is between 2-8°C, and it should be protected from strong oxidizing agents to maintain stability and purity.