3-Aminobenzenesulfonamide

Basic Information

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CAS Number

98-18-0

Molecular Formula

C6H8N2O2S

Molecular Weight

172.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

140.0 to 144.0 deg-C

Boiling Point

420.7°C at 760 mmHg

Density

1.303 (estimate)

Flash Point

208.3 °C

Refractive Index

1.6490 (estimate)

SMILES

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C1=CC(=CC(=C1)S(=O)(=O)N)N

InChI

InChI=1S/C6H8N2O2S/c7-5-2-1-3-6(4-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)

InChIKey

JPVKCHIPRSQDKL-UHFFFAOYSA-N

LogP

-0.08379999999999999

Topological Polar Surface Area

86.18 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

219

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

Benzenesulfonamide, 3-amino-
NS00040526
m-sulfamylaniline
3-Aminosulfonylaniline
Aminobenzenesulfonamide, 3-
SCHEMBL189005
Metanilamide
3-Amino Benzenesulfonamide
SY048182
BDBM50079047
BRN 0511851
D77854
F0728-0012
EINECS 202-646-0
3-sulfamoyl-aniline
CHEMBL6852
AKOS000298884
m-Amino benzene sulfonanilide
3-Aminobenzene-1-Sulfonamide
3-aminobenzene sulfonamide
DTXSID5059161
FT-0615023
3-aminobenzene-sulfonamide
3-AMINOBENZENESULFONAMIDE
W-100089
DW73A2TD9A
1-aminobenzene-3-sulfonamide
3-Aminobenzenesulphonamide
3-sulfamoyl-phenylamine
MFCD00035781
SDCCGMLS-0066234.P001

MDL Number

MFCD00035781

Customs Code

2935009090

FAQ

What are the physical and chemical properties of 3-Aminobenzenesulfonamide (CAS: 98-18-0)?

3-Aminobenzenesulfonamide (CAS: 98-18-0) is a white crystalline solid with a molecular weight of 178.19 g/mol. It is slightly soluble in water and ethanol. The compound is relatively stable but can undergo hydrolysis in aqueous solutions. It is an amine derivative and can react with acids to form salts. It is also susceptible to oxidation in air and light.

How is 3-Aminobenzenesulfonamide (CAS: 98-18-0) typically synthesized?

3-Aminobenzenesulfonamide (CAS: 98-18-0) is typically synthesized via the reaction of 3-chlorobenzenesulfonamide with ammonia or an amine in the presence of a base such as sodium hydroxide. The reaction involves the nucleophilic substitution of the chlorine with an amino group. Common methods also include direct amination of benzenesulfonamide derivatives.

What industries use 3-Aminobenzenesulfonamide (CAS: 98-18-0)?

3-Aminobenzenesulfonamide (CAS: 98-18-0) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of drugs. It is also utilized in the production of polymers, dyes, and as a reagent in analytical chemistry for the detection of organic compounds. In addition, it is employed in the preparation of semiconductors and as a component in certain sensors.

What precautions should be taken when handling 3-Aminobenzenesulfonamide (CAS: 98-18-0)?

When handling 3-Aminobenzenesulfonamide (CAS: 98-18-0), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and laboratory coat. Work in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials. In case of skin contact, wash with plenty of water. For ingestion, do not induce vomiting and seek medical attention immediately. Always refer to the Safety Data Sheet (SDS) for detailed information and emergency procedures.