3-Bromo-5-methylpyridin-4-amine

Basic Information

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CAS Number

97944-43-9

Molecular Formula

C6H7BrN2

Molecular Weight

187.04 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

290°Cat760mmHg

Density

1.593

Flash Point

129.2°C

Refractive Index

1.617

SMILES

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CC1=CN=CC(=C1N)Br

InChI

InChI=1S/C6H7BrN2/c1-4-2-9-3-5(7)6(4)8/h2-3H,1H3,(H2,8,9)

InChIKey

GUAFGBUKLIFASX-UHFFFAOYSA-N

LogP

1.7347199999999998

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

97.1

Synonyms & References

English

3-Bromo-5-methylpyridin-4-amine
4-Amino-5-bromo-3-methylpyridine
4-Pyridinamine,3-bromo-5-methyl-
4-Amino-3-bromo-5-methylpyridine
4-Pyridinamine, 3-bromo-5-methyl-
3-Bromo-5-methyl-pyridin-4-ylamine
3-BROMO-5-METHYL-4-PYRIDINAMINE
PubChem17044
4-Amino-5-bromo-3-picoline
GUAFGBUKLIFASX-UHFFFAOYSA-N
6846AC
3-BROMO-5-METHYL-4-PYRIDYLAMINE
BC004191
3-Bromo-5-methyl-4-pyridinamine (ACI)
3-Bromo-5-methyl-1,4-dihydropyridin-4-imine
3-bromo-5-methyl-pyridin-4-amine
DTXSID90540243
EN300-105074
CS-0042800
SY066924
DB-024936
AKOS006284117
SB40341
GS-5725
97944-43-9
MFCD07437841
SCHEMBL23234761
Z1198173286
AC-33416
SCHEMBL14206718

MDL Number

MFCD07437841

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 3-Bromo-5-methylpyridin-4-amine (CAS: 97944-43-9)?

3-Bromo-5-methylpyridin-4-amine is a crystalline solid with a molecular weight of approximately 228.04 g/mol. It has a high solubility in organic solvents like ethanol and acetone but is less soluble in water. The compound is moderately reactive and can undergo substitution reactions with nucleophiles. It is stable under normal conditions but should be stored away from strong oxidizing agents and heat sources.

How is 3-Bromo-5-methylpyridin-4-amine (CAS: 97944-43-9) typically synthesized?

3-Bromo-5-methylpyridin-4-amine is typically synthesized by reacting 5-bromo-3-methylpyridin-4-amine with methyl bromide in the presence of a base like sodium hydride. The reaction is carried out in anhydrous conditions to avoid side reactions. The process yields a product with high selectivity and purity, suitable for further applications.

What industries use 3-Bromo-5-methylpyridin-4-amine (CAS: 97944-43-9)?

3-Bromo-5-methylpyridin-4-amine is used in various industries, particularly in the pharmaceutical sector for the development of new drugs. It is also utilized in the synthesis of some organic polymers and as a reagent in sensor technology due to its unique chemical properties.

What precautions should be taken when handling 3-Bromo-5-methylpyridin-4-amine (CAS: 97944-43-9)?

When handling 3-Bromo-5-methylpyridin-4-amine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be carefully cleaned up using appropriate absorbents, and the area should be ventilated. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.