4-(4-Chlorophenoxy)piperidine

Basic Information

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CAS Number

97839-99-1

Molecular Formula

C11H14ClNO

Molecular Weight

211.69 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Water Solubility

Slightly soluble in water.

SMILES

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C1CNCCC1OC2=CC=C(C=C2)Cl

InChI

InChI=1S/C11H14ClNO/c12-9-1-3-10(4-2-9)14-11-5-7-13-8-6-11/h1-4,11,13H,5-8H2

InChIKey

VOQMPZXAFLPTMM-UHFFFAOYSA-N

LogP

2.4708000000000006

Topological Polar Surface Area

21.259999999999998 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

163

Synonyms & References

English

AMY11553
AB17687
4-(4-chlorophenoxy)piperidine
EN300-316861
BB 0220528
AKOS004910774
FT-0759814
4-(4-chloro-phnenoxy)-piperidine
CS-0132427
4-(4-Chloro-Phenoxy)-Piperidine
A853688
MFCD04113544
N-OCTADECYLPHOSPHONICACID
97839-99-1
4-(p-chlorophenoxy)piperidine
SCHEMBL187857
PIPERIDINE,4-(4-CHLOROPHENOXY)-
DTXSID50409408
VOQMPZXAFLPTMM-UHFFFAOYSA-N
4-[(4-chlorophenyl)oxy]piperidine
E81599
4-(4-Chlorophenoxy)piperidine
4-(4-chlorophenoxy)-piperidine
4-(4-chlorophenoxy)piperidine(SALTDATA: HCl)
4-(4-Chloro-phenoxy)-piperidine

MDL Number

MFCD04113544

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 4-(4-Chlorophenoxy)piperidine (CAS: 97839-99-1)?

4-(4-Chlorophenoxy)piperidine is a white crystalline solid with a molecular weight of approximately 265.64 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. This compound is reactive and can undergo substitution reactions. It has a pKa of about 8.5, indicating basic behavior.

How is 4-(4-Chlorophenoxy)piperidine (CAS: 97839-99-1) typically synthesized?

4-(4-Chlorophenoxy)piperidine is typically synthesized via the condensation of 4-chlorophenol with piperidine, often catalyzed by a transition metal like copper. The reaction involves the formation of an intermediate ester, which is then hydrolyzed to the final piperidine derivative. This process provides good yield and selectivity.

What industries use 4-(4-Chlorophenoxy)piperidine (CAS: 97839-99-1)?

4-(4-Chlorophenoxy)piperidine is used in the pharmaceutical industry for the synthesis of certain drugs, particularly those that require specific functional groups. It is also utilized in the polymer industry for modifying materials and in sensor technology for detecting specific chemical species.

What precautions should be taken when handling 4-(4-Chlorophenoxy)piperidine (CAS: 97839-99-1)?

When handling 4-(4-Chlorophenoxy)piperidine, appropriate personal protective equipment (PPE) must be worn, including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from heat sources and strong acids. In case of a spill, it should be cleaned up using appropriate absorbents, and the area should be ventilated. Safety data sheets (SDS) should always be consulted for detailed handling instructions.