Bendamustine Hydrochloride

Basic Information

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CAS Number

97832-05-8

Molecular Formula

C16H22Cl3N3O2

Molecular Weight

394.7 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl

InChI

InChI=1S/C16H21Cl2N3O2.ClH/c1-20-14-6-5-12(21(9-7-17)10-8-18)11-13(14)19-15(20)3-2-4-16(22)23;/h5-6,11H,2-4,7-10H2,1H3,(H,22,23);1H

InChIKey

ZHSKUOZOLHMKEA-UHFFFAOYSA-N

LogP

3.686400000000003

Topological Polar Surface Area

58.36 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

380

Synonyms & References

English

Treanda (TN)
Cytostosan
Ribomustin
2-Benzimidazolinebutryric acid, hydrochloride
Fmoc-(S)-3-Amino-3-(3-trifluoromethyl-phenyl)-propionicacid
BENDAMUSTINE HYDROCHLORIDE [ORANGE BOOK]
Cytostasan
SMR004234484
SB17462
Hydrochloride, Bendamustine
Q27272066
VIVIMUSTA
3543-75-7
MFCD16879055
Treakisym
4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzoimidazol-2-yl)butanoic acid monohydrochloride
5-[Bis(2-chloroethyl)-amino]-1-methyl-1H-benzimidazole-2-butanoic Acid Hydrochloride;Ribomustin HCl
1H-Benzimidazole-2-butanoic acid, 5-(bis(2-chloroethyl)amino)-1-methyl-, monohydrochloride
AS-15856
1H-Benzimidazole-2-butanoic acid, 5-[bis(2-chloroethyl)amino]-1-methyl monohydrochloride
IMET 3393
Bendamustine hydrochloride [USAN:JAN]
DTXCID00111403
ZIMET 33/93
2-Benzimidazolebutyric acid, 5-(bis(2-chloroethyl)amino)-1-methyl-, monohydrochloride
WLN: T56 BN DNJ B1 C3VQ GN2G2G &GH
SDX-105 (Cytostasane) HCl
Bendamustine hydrochloride
Symbenda
Tox21_500623
UNII-981Y8SX18M

FAQ

What is Bendamustine Hydrochloride (CAS: 97832-05-8)?

Bendamustine Hydrochloride (CAS: 97832-05-8) is an alkylating agent used in chemotherapy. It consists of bendamustine, a nitrogen mustard derivative, and hydrochloride salt. This compound has a molecular formula of C15H13N5O2·HCl and is water-soluble, which makes it suitable for intravenous administration.

What are the main uses of Bendamustine Hydrochloride (CAS: 97832-05-8)?

Bendamustine Hydrochloride (CAS: 97832-05-8) is primarily used in the treatment of hematological malignancies, such as chronic lymphocytic leukemia (CLL) and indolent non-Hodgkin lymphoma. It is also utilized in combination with other chemotherapeutic agents.

Is Bendamustine Hydrochloride (CAS: 97832-05-8) safe?

Bendamustine Hydrochloride (CAS: 97832-05-8) can be safe when used under medical supervision. However, it requires careful management due to potential side effects like nausea, vomiting, and bone marrow suppression. Patients must follow medical advice and adhere to safety guidelines to minimize risks.

How should Bendamustine Hydrochloride (CAS: 97832-05-8) be stored?

Bendamustine Hydrochloride (CAS: 97832-05-8) should be stored in a tightly closed container at room temperature (15-30°C) and protected from light. It should be kept away from heat, moisture, and direct sunlight to ensure stability and safety.