Cefepime, E- | CAS No. 97164-57-3

Cefepime, E-

Basic Information

CAS Number

97164-57-3

Molecular Formula

C19H24N6O5S2

Molecular Weight

480.56 g/mol

AD

Basic Physical Properties

C[N+]1(CCCC1)CC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)[O-]

InChI

1S/C19H24N6O5S2/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29)/b23-12+/t13-,17+/m1/s1

InChIKey

HVFLCNVBZFFHBT-WISACFTLSA-N

Complexity

869

Synonyms & References

English

  • Anticefepime
  • Cefepime Impurity A
  • (6R,7R)-7-((E)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((1-methylpyrrolidin-1-ium-1-yl)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • Cefepime EP Impurity A
  • UNII-Z0114Q3738
  • F82041
  • 149261-27-8
  • Z0114Q3738
  • cefepime
  • (6R,7R)-7-[[(2E)-2-(2-aminothiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • Cefepime, E-
  • Cefepime specified impurity A [EP]
  • 88040-23-7
  • DTXSID70873208
  • [6R-[6.alpha.,7.beta.(Z)]]-1-[[7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methylpyrrolidinium, hydroxide, inner salt
  • CEFEPIME DIHYDROCHLORIDE MONOHYDRATE IMPURITY A [EP IMPURITY]
  • Anti-cefepime
  • Cefepime, Antibiotic for Culture Media Use Only
  • HVFLCNVBZFFHBT-ZKDACBOMSA-N
  • E-Cefepime
  • 97164-57-3
  • Maxipime
  • W-204251
  • GTPL10772
  • BIDD:GT0809
  • CEFEPIME IMPURITY A [EP IMPURITY]
  • SCHEMBL98274
  • PYRROLIDINIUM, 1-((7-(((2-AMINO-4-THIAZOLYL)(METHOXYIMINO)ACETYL)AMINO)-2-CARBOXY-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-EN-3-YL)METHYL)-1-METHYL-, (6R-(6.ALPHA.,7.BETA.(E)))-
  • Cefepime, BMY-2
  • (6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • AKOS015895225

MDL Number

MFCD28143514

FAQ

What regulatory guidelines apply to Cefepime (CAS: 97164-57-3)?

Cefepime (CAS: 97164-57-3) falls under the regulatory guidelines of the REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) regulation in the EU, and the Toxic Substances Control Act (TSCA) in the USA under the EPA (Environmental Protection Agency). It is also subject to FDA (Food and Drug Administration) regulations for the approval and marketing of pharmaceuticals. Proper labeling and documentation are required according to GHS (Globally Harmonized System of Classification and Labelling of Chemicals) guidelines.

Are there alternatives to Cefepime (CAS: 97164-57-3) in synthesis?

While Cefepime (CAS: 97164-57-3) is a powerful antibiotic, other cephalosporins such as ceftriaxone and cefoperazone can be considered alternatives in certain synthetic pathways. Isomers and analogs like cefotetan can also be explored, but it is important to evaluate their effectiveness and regulatory compliance before use.

What is the market or research trend for Cefepime (CAS: 97164-57-3)?

The market for Cefepime (CAS: 97164-57-3) is robust, driven by its broad-spectrum antibacterial activity and low risk of cross-resistance with other β-lactam antibiotics. Research trends focus on its use in treating multidrug-resistant infections and its potential in combination therapies. However, there is a growing interest in developing newer and more potent cephalosporins to counter the increasing resistance.

How should waste containing Cefepime (CAS: 97164-57-3) be handled?

Waste containing Cefepime (CAS: 97164-57-3) should be collected in appropriate, leak-proof containers and stored in a secure, well-ventilated area. Disposal should be handled by a professional waste management company due to its potential for environmental contamination. Incineration is a common method for proper disposal, and all handling should comply with local and federal regulations to minimize environmental impact.

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