Cisatracurium Besylate

Basic Information

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CAS Number

96946-42-8

Molecular Formula

C65H82N2O18S2

Molecular Weight

1243.48 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

93-102°C

Boiling Point

No data available

Flash Point

No data available

Solubility

H2O: soluble1mg/mL

Vapor Pressure

No data available

SMILES

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C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C=C1)S(=O)(=O)[O-]

InChI

InChI=1S/C53H72N2O12.2C6H6O3S/c1-54(22-18-38-32-48(62-7)50(64-9)34-40(38)42(54)28-36-14-16-44(58-3)46(30-36)60-5)24-20-52(56)66-26-12-11-13-27-67-53(57)21-25-55(2)23-19-39-33-49(63-8)51(65-10)35-41(39)43(55)29-37-15-17-45(59-4)47(31-37)61-6;2*7-10(8,9)6-4-2-1-3-5-6/h14-17,30-35,42-43H,11-13,18-29H2,1-10H3;2*1-5H,(H,7,8,9)/q+2;;/p-2/t42-,43-,54-,55-;;/m1../s1

InChIKey

XXZSQOVSEBAPGS-DONVQRBFSA-L

LogP

11.32610

Complexity

1560

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

Cisatracurium besilate
(1r,1'r,2r,2'r)-2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinolinium dibenzenesulfonate
cisatracurium besylate
1R-CIS,1R∧-CIS (CISATRACURIUM BESYLATE)
Cisatracurium
3-[(1R,2R)-6,7-dimethoxy-2-methyl-1-veratryl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propionic acid 5-[3-[(1R,2R)-6,7-dimethoxy-2-methyl-1-veratryl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl ester
5-[3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate
Cisatracurium Besilete
(1R,1'R)-atracurium besylate
(1R,1'R,2R,2'R)
1R,1R'-2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl) methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium] dibenzenesulfonate
Cisatracurium (besylate)
Cisatracurium besyla
Cis-AttacuriuM
atracurium
Cisatracurium besi
81NKC0O7PC
(1R,2R,1'S,2'S)-atracurium besylate
51W89
Atracurium besylate, (1R,2R,1'S,2'S)-
benzenesulfonate; 5-[3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[(1S,2S)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propan
Isoquinolinium, 2,2'-(1,5-pentanediylbis(oxy(3-oxo-3,1-propanediyl)))bis(1-((3,4-dimethoxyphenyl)methyl)-1,2,3,4
Nimbex
80YS8O1MBS
(1R,1'R,2R,2'R)-2,2'-((pentane-1,5-diylbis(oxy))bis(3-oxopropane-3,1-diyl))bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium) benzenesulfonate
(1R-cis,1'R-cis)-Atracurium besylate
Cisatracurium besilate (INN)
Cisatracurium besilate [INN]
NIMBEX PRESERVATIVE FREE
Cis-Atracurium Besylate
Nimbium

MDL Number

MFCD00871018

Customs Code

2914509090

FAQ

What is Cisatracurium Besylate (CAS: 96946-42-8)?

Cisatracurium Besylate (CAS: 96946-42-8) is a non-depolarizing neuromuscular blocking agent used in medical settings. Its chemical formula is C23H42N2O12S2, and it appears as a white, crystalline powder. It is insoluble in water but soluble in organic solvents. This compound works by competitively inhibiting acetylcholine receptors at the neuromuscular junction, inducing muscle relaxation for surgical procedures.

What are the main uses of Cisatracurium Besylate (CAS: 96946-42-8)?

Cisatracurium Besylate (CAS: 96946-42-8) is primarily used in anesthesia to induce skeletal muscle relaxation, facilitating intubation and surgery. It is also employed in critical care for patients requiring controlled muscle paralysis. Additionally, it serves as a research tool in pharmacology to study neuromuscular transmission and as a component in veterinary medicine for animal sedation and surgery.

Is Cisatracurium Besylate (CAS: 96946-42-8) safe?

Cisatracurium Besylate (CAS: 96946-42-8) is safe when administered by trained healthcare professionals under medical supervision. However, it may cause respiratory depression, requiring careful monitoring. Safety standards include adherence to FDA and WHO guidelines. Precautions involve avoiding overdose and ensuring proper ventilation during use to mitigate risks.

How should Cisatracurium Besylate (CAS: 96946-42-8) be stored?

Cisatracurium Besylate (CAS: 96946-42-8) should be stored at controlled room temperature (20-25°C) in a cool, dry place away from light. It requires airtight packaging to prevent moisture exposure and degradation. Stability is maintained under these conditions, and storage should follow manufacturer guidelines to ensure potency and safety.