Opromazine | CAS No. 969-99-3

Opromazine

Basic Information

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CAS Number

969-99-3

Molecular Formula

C17H19ClN2OS

Molecular Weight

334.87 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

115°

Boiling Point

502.6°Cat760mmHg

Density

1.35

Flash Point

257.8°C

Refractive Index

1.687

SMILES

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CN(C)CCCN1C2=CC=CC=C2S(=O)C3=C1C=C(C=C3)Cl

InChI

InChI=1S/C17H19ClN2OS/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)22(21)17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3

InChIKey

QEPPAOXKZOTMPM-UHFFFAOYSA-N

LogP

3.909900000000003

Topological Polar Surface Area

23.55 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

406

Safety Information

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Toxicity

LD50 s.c. in mice: 102 mg/kg (Minami, Yoshimoto)

Synonyms & References

English

10H-Phenothiazine-10-propanamine,2-chloro-N,N-dimethyl-, 5-oxide
Chlorpromazine Sulfoxide
3-(2-chloro-5-oxophenothiazin-10-yl)-N,N-dimethylpropan-1-amine
CHLORPROMAZINE SULFOXIDE, BP STANDARD
Chloropromazine sulfoxide
Chlorpromazine sulphoxide
Chlorpromazine-S-oxide
Chlorpromazine-S-oxyd
Opromazin
Opromazine
Oxychlorpromazine
Secotil
Transedon
3-(2-Chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1- amine S-oxide
Phenothiazine, 2-chloro-10-[3-(dimethylamino)propyl]-, 5-oxide (6CI, 8CI)
Aminazin sulfoxide
Ba 2835
Chlorpromazine 5-oxide
Chlorpromazine 5-sulfoxide
Chlorpromazine S-oxide
Chlorpromazine sulfoxide
NSC 170990
2-Chloro-10-(3-(dimethylamino)propyl)-10H-phenothiazine 5-oxide
10H-Phenothiazine-10-propanamine,N-dimethyl-, 5-oxide
DTXSID40871817
10-(.gamma.-Dimethylaminopropyl)-3-chlorophenothiazine 9-oxide
10-(.GAMMA.-DIMETHYLAMINOPROPYL)-3-CHLORPHENOTHIAZINE 9-OXIDE
CHEMBL823
2-Chloro-10-(3-(dimethylamino)propyl)phenothiazine-5-oxide
2-CHLORO-10-(3-(DIMETHYLAMINO)PROPYL)PHENOTHIAZINE 5-OXIDE
CPZ-SO

MDL Number

MFCD01706964

FAQ

What regulatory guidelines apply to opromazine (CAS: 969-99-3)?

Opromazine (CAS: 969-99-3) is subject to various regulatory guidelines. It should comply with the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), which includes health, environmental, and physical hazard classifications. Additionally, it adheres to REACH regulations in the European Union, which require registration, evaluation, and authorization of substances. In the United States, it must meet FDA and EPA requirements for safety and environmental protection.

Are there alternatives to opromazine (CAS: 969-99-3) in synthesis?

Yes, alternatives to opromazine (CAS: 969-99-3) in synthesis include other antipsychotic drugs such as haloperidol and clozapine. These analogs often have similar pharmacological profiles but may differ in potency and side effects. Common alternative reagents in synthesis include substituted pyrimidines and piperazines, which can offer improved synthetic pathways with better yields and selectivity.

What is the market or research trend for opromazine (CAS: 969-99-3)?

The research trend for opromazine (CAS: 969-99-3) focuses on its potential applications in treating psychiatric disorders. Market trends suggest increased interest in understanding its mechanisms of action and exploring its therapeutic potential in combination with other medications. Recent studies have also investigated its use in managing symptoms of schizophrenia and other psychotic disorders, with ongoing research focusing on optimizing its efficacy and reducing side effects.

How should waste containing opromazine (CAS: 969-99-3) be handled?

Waste containing opromazine (CAS: 969-99-3) should be collected in appropriate containers and stored in a secure location. It should be disposed of through professional waste disposal services that comply with local regulations. Incineration is a common method for waste disposal, but proper environmental precautions must be taken to minimize pollution. Environmental protection measures include monitoring air and water quality, and using neutralization techniques to prevent hazardous material from entering the environment.